What are the effects of wet beriberi?

• A. Severe confusion and behavior changes
• B. Heart failure and edema
• C. Peripheral neuropathy and skin lesions
• D. Ataxia and visual impairment

Answer: (B)

Wet beriberi is primarily associated with thiamine (vitamin B1) deficiency and is characterized by cardiovascular manifestations, particularly heart failure, and significant fluid retention leading to edema. The deficiency disrupts the metabolism of carbohydrates, causing buildup of pyruvate and lactate, which can strain heart function and lead to symptoms like an enlarged heart, rapid heartbeat, and swelling due to fluid accumulation in tissues.

This condition stands in contrast to the neurological manifestations of dry beriberi, which is more closely linked to peripheral neuropathy and other central nervous system symptoms. Thus, the primary effects of wet beriberi align closely with cardiovascular issues, making heart failure and edema the hallmark signs of this specific deficiency state.